Acidente Isquémico Transitório e Angiopatia Amiloide Cerebral Associada a Inflamação: Apresentação Semelhante, Entidades Diferentes
DOI:
https://doi.org/10.46531/sinapse/CC/230085/2024Palavras-chave:
Acidente Isquémico Transitório, Angiopatia Amiloide Cerebral, Ressonância MagnéticaResumo
Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a rare subtype of CAA characterized by a perivascular inflammatory response to amyloid deposition in the brain.
The authors detail the case of a 74-year-old man with aphasia, who was diagnosed with probable CAA-ri following brain magnetic resonance imaging. Treatment recom- mendations included a 5-day course of high-dose methylprednisolone.
CAA-ri may manifest with transient or permanent neurological symptoms resem- bling a transient ischemic attack or stroke, potentially leading to misdiagnosis and inadequate long-term treatment. Hence, our objective is to highlight the clinical and imaging findings of this case.
Downloads
Referências
Ronsin S, Deiana G, Geraldo AF, Durand-Dubief F, Thomas-Maisonneuve L, Formaglio M, et al. Pseudotumoral presentation of cerebral amyloid angiopathy-related inflammation. Neurology. 2016;86:912-9. doi: 10.1212/ WNL.0000000000002444.
Martucci M, Sarria S, Toledo M, Coscojuela P, Vert C, Siurana S, et al. Cerebral amyloid angiopathy-related inflammation: imaging findings and clinical outcome. Neuroradiology. 2014;56:283-9. doi: 10.1007/s00234-014-1330-6.
Kirshner HS, Bradshaw M. The Inflammatory Form of Cerebral Amyloid Angiopathy or “Cerebral Amyloid Angiopa-thy-Related Inflammation” (CAARI). Curr Neurol Neurosci Rep. 2015;15:54. doi: 10.1007/s11910-015-0572-y.
Theodorou A, Palaiodimou L, Malhotra K, Zompola C, Katsanos AH, Shoamanesh A, et al. Clinical, Neuroimaging,
and Genetic Markers in Cerebral Amyloid Angiopathy-Related Inflammation: A Systematic Review and Meta-Analysis. Stroke. 2023;54:178-88. doi: 10.1161/STROKEAHA.122.040671.
Chung KK, Anderson NE, Hutchinson D, Synek B, Barber PA. Cerebral amyloid angiopathy related inflammation: three case reports and a review. J Neurol Neurosurg Psy-chiatry. 2011;82:20-6. doi: 10.1136/jnnp.2009.204180.
Auriel E, Charidimou A, Gurol ME, Ni J, Van Etten ES, Martinez-Ramirez S, et al. Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA Neurol. 2016;73:197-202. doi: 10.1001/jamaneurol.2015.4078.
Regenhardt RW, Thon JM, Das AS, Thon OR, Charidimou A, Viswanathan A, et al. Association Between Immunosuppressive Treatment and Outcomes of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA Neurol. 2020;77:1261-9. doi: 10.1001/jamaneurol.2020.1782.
Yamada M. Cerebral amyloid angiopathy: emerging concepts. J Stroke. 2015;17:17-30. doi: 10.5853/ jos.2015.17.1.17.
Coulette S, Renard D, Lehmann S, Raposo N, Arquizan C, Charif M, et al. A Clinico-Radiological Study of Cerebral Amyloid Angiopathy-Related Inflammation. Cerebrovasc Dis. 2019;48:38-44. doi: 10.1159/000502832.
Antolini L, DiFrancesco JC, Zedde M, Basso G, Arighi A, Shima A, et al. Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study. Neurology. 2021;97):e1809-22. doi: 10.1212/WNL.0000000000012778.
Downloads
Publicado
Como Citar
Edição
Secção
Licença
Direitos de Autor (c) 2024 Raquel Oliveira, Raquel Batista, Priscila Flores, Ana Massano, Sérgio Galo, Isabel Martins
Este trabalho encontra-se publicado com a Creative Commons Atribuição-NãoComercial 4.0.
