Tumor Recurrence versus Radiation-induced Stroke in a Child with a History of Medulloblastoma
DOI:
https://doi.org/10.46531/sinapse/CC/220076/2023Keywords:
Child, Medulloblastoma/radiotherapy, Radiation Injuries/ complications, Stroke/etiologyAbstract
Children with a history of central nervous system neoplasia, submitted to radiotherapy, have an increased risk of vascular complications that can be, clinically and imagiologically, very similar to a tumor recurrence. We describe the case of an 11-year-old child who, 10 years after diagnosis and treatment of a medulloblastoma, suddenly developed right hemiparesis. The initial imaging findings did not allow the exclusion of tumor recurrence, making a differential diagnosis with recent ischemic injury. Due to clinical and imaging worsening, the patient started chemotherapy, suspended after the first cycle, due to clear neurological improvement. One month after the onset of symptoms, patient was clinically stable, having undergone a new magnetic resonance imaging, revealing a chronic evolution of the lesion, suggestive of a vascular etiology. This case explores the differential diagnosis of late tumor recurrence in children undergoing radiotherapy, highlighting the importance of etiological identification in therapeutic guidance.Downloads
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