Hemiathetosis-Hemichorea as Initial Manifestation of Brain Metastases from Urothelial Carcinoma
DOI:
https://doi.org/10.46531/sinapse/CC/246/2026Keywords:
Brain Neoplasms/secondary, Carcinoma, Transitional Cell/secondary, Chorea/etiology, Movement Disorders/etiology, Urinary Bladder NeoplasmsAbstract
Brain metastases rarely present with movement disorders. We report a case of a 77-year-old woman with invasive urothelial carcinoma who developed right hemichorea-hematitestosis as the initial manifestation of multiple brain metastases. The patient presented to the emergency department with behavioral changes, disorientation, and involuntary movements of the right hemibody lasting five hours. Brain magnetic resonance imaging revealed multiple intra-axial secondary lesions, including a left subthalamic lesion. She was treated with dexamethasone and haloperidol for symptomatic control. The patient died three weeks after admission. This case illustrates a rare presentation of brain metastases and reinforces the importance of considering neoplasia in the differential diagnosis of acute-onset hemicorhea-hemiathetosis, particularly in oncological patients.
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Copyright (c) 2024 Manuel Maia, Nathalia Ferreira, Ricardo Velho, José Brito, Pedro Faustino
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