About the Journal

SINAPSE is an international peer-reviewed journal for physicians treating individuals with neurological diseases and other healthcare professionals interested in the structure and function of the normal and diseased nervous system. The target audience of the journal includes physicians, nurses, nutritionists, pharmacists, psychologists, physiotherapists, epidemiologists, clinical researchers, other specialists involved in healthcare (including management and administration), and scientists in basic and translational fields.

Current Issue

Vol. 25 No. 4 (2025): October - December
View Vol. 25 No. 4 (2025): October - December
Published: 2026-01-04

Editorial

  • The Alien Neurology

    João Martins
    155-157
    DOI: https://doi.org/10.46531/sinapse/ED/200/2025

  • Thanking Sinapse Peer Reviewers

    Filipe Palavra
    158
    DOI: https://doi.org/10.46531/sinapse/ED/204/2025

Original Articles

  • Age-Related Normative Data and Percentile Ranges for Serum Neurofilament Light Chain Levels

    Anuschka Silva-Spínola, Miguel Tábuas-Pereira, Maria João Leitão, Catarina Bernardes, Marisa Lima, João Durães, Sandra Freitas, Isabel Santana, Inês Baldeiras
    159 - 163
    DOI: https://doi.org/10.46531/sinapse/AO/150/2025

  • Dopaminergic Infusion Therapies in Parkinson’s Disease: Real-World Data from a Portuguese Center

    Sofia Lopes, Margarida Silva, Andreia Ferreira, Oc´távia Costa, Gisela Carneiro, Margarida Rodrigues, Sara Varanda
    164 - 171
    DOI: https://doi.org/10.46531/sinapse/AO/160/2025

Case Reports

  • PRRT2-Associated Disorders: A Phenotypic Spectrum of Paroxysms

    Catarina Bernardes, Constança Santos, Joana Amaral , Filipe Palavra, Cristina Pereira, Joana Ribeiro
    172 - 177
    DOI: https://doi.org/10.46531/sinapse/CC/134/2025

  • Clinical and Molecular Delineation of AHI1-Associated Joubert Syndrome in a Consanguineous Pedigree: A Case Report

    Doaa Haqi Ismael, Almuthana K. Hameed, Shaymaa Muneam Saeed, Sahar Kareem Al-Mozani, Kamele Jorfi, Motahareh Sheikh-Hosseini, Ehab Neissi
    178 - 185
    DOI: https://doi.org/10.46531/sinapse/CC/169/2025

  • Non-Alcohol-Related Wernicke Encephalopathy

    Rita Nunes Rato, Bárbara Martins, Carolina Correia, Carolina Soares, Andreia Costa
    186 - 190
    DOI: https://doi.org/10.46531/sinapse/CC/137/2025

  • Primary Central Nervous System Lymphoma Mimicking Neuro-Behcet Disease

    Lénia Silva, Sara Costa, Liliana Igreja, Ricardo Taipa, João Araújo Correia, Ernestina Santos
    191 - 195
    DOI: https://doi.org/10.46531/sinapse/CC/165/2025

  • Infantile Neuroaxonal Dystrophy: Clinical Case

    Filipa Alveirinho, Inês Noites, Carla Conceição, Ana Luísa Rodrigues, Eulália Viveiros
    196 - 199
    DOI: https://doi.org/10.46531/sinapse/CC/149/2025

  • Bilateral Optic Neuropathy as First Manifestation of Tuberculosis

    Luís Rufo Costa, Rui Pedro Silva, Sara Gomes, Isabel Amorim, Ana Filipa Santos, Gonçalo Cação, Cristina Almeida, Célia Machado
    200 - 204
    DOI: https://doi.org/10.46531/sinapse/CC/195/2025

  • A Family with Subclinical Charcot-Marie-Tooth Disease Associated with a Mutation in the MPZ Gene

    Beatriz Madureira, Isa Correia, Hildeberto Correia, Simão Cruz
    205 - 209
    DOI: https://doi.org/10.46531/sinapse/CC/121/2025

Guidelines

Images in Neurology

  • Red Flag: When Motor Potentials are Small without an Apparent Cause

    Patricia Grilo, Sandra Palma , Cristiana Alves , Pedro Pereira
    227 - 228
    DOI: https://doi.org/10.46531/sinapse/IN/126/2025

  • Status Epilepticus Amauroticus

    Ana João Marques, Rafael Jesus, Pedro Guimarães, João Paulo Gabriel
    229 - 230
    DOI: https://doi.org/10.46531/sinapse/IN/93/2025
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