Radiologically Isolated Syndrome in Pediatric Age: The Ideal Clinical Model for the Study of Remyelination?
DOI:
https://doi.org/10.46531/sinapse/AR/210032/2022Keywords:
Child, Magnetic Resonance Imaging, Multiple SclerosisAbstract
Radiologically isolated syndrome (RIS) is a condition in which imagiological findings suggestive of demyelination, specifically multiple sclerosis, are seen in neurologically asymptomatic individuals. Hence, RIS is usually referred to as a pre-symptomatic stage of multiple sclerosis, making it an interesting research object, with the goal of modifying the risk of subsequent evolution to that demyelinating disease. RIS can be diagnosed in children and adolescents, but the data available on this condition for this age range is still scarce. This review on pediatric RIS focuses on the benefit of its research, specifically aiming at the eventual development of therapeutic interventions that, in the future, will eventually promote remyelination and neuroprotection.Downloads
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